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N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos
https://repository.naro.go.jp/records/186
https://repository.naro.go.jp/records/18631d2afe9-641f-41a3-8027-9485cc360c0a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
SC10201706140010_CCBYNCND_ja.pdf (522.9 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-02-05 | |||||
| タイトル | ||||||
| タイトル | N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos | |||||
| タイトル | ||||||
| タイトル | N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Antioxidant | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Bovine embryo | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | DMG | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | In vitro fertilization | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | N, N-Dimethylglycine | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Antioxidant | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Bovine embryo | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | DMG | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | In vitro fertilization | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | N, N-Dimethylglycine | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
TAKAHASHI, Toshikiyo
× TAKAHASHI, Toshikiyo× SASAKI, Kouya× SOMFAI, Tamas× NAGAI, Takashi× MANABE, Noboru× EDASHIGE, Keisuke |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The antioxidant effect of N, N-dimethylglycine (DMG) on in vitro-produced (IVP) bovine embryos was examined. After in vitro fertilization, presumptive zygotes were cultured with or without 0.1 μM DMG under different oxygen tensions. The percentage of embryos developing to the blastocyst stage was lowest under a 20% oxygen concentration without DMG, and it was significantly increased (P < 0.05) by applying a 5% oxygen concentration. Under the 20% oxygen concentration, supplementation of the medium with DMG significantly improved blastocyst development, which was nearly equal to that achieved under 5% oxygen without DMG. Furthermore, a tendentious increase (P = 0.06) in blastocyst cell numbers was observed when DMG was applied. In the second experiment, addition of H2O2 (0.5 mM) to the culture medium significantly (P < 0.01) reduced the percentage of embryos developing to the blastocyst stage. However, DMG supplementation prevented this reduction. In conclusion, DMG enhanced the invitro development of IVP bovine embryos by acting as an antioxidant. | |||||
| 書誌情報 |
Journal of Reproduction and Development en : Journal of Reproduction and Development 巻 62, 号 2, p. 209-212, 発行日 2016 |
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| 出版者 | ||||||
| 出版者 | Society for Reproduction and Development | |||||
| 出版者 | ||||||
| 出版者 | 日本繁殖生物学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1348-4400 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 26875568 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1262/jrd.2015-149 | |||||
| 権利 | ||||||
| 権利情報 | (c)2016 Society for Reproduction and Development | |||||
| 権利 | ||||||
| 権利情報 | (c) 日本繁殖生物学会 | |||||
| 情報源 | ||||||
| 関連名称 | SC10201706140010 | |||||
| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1262/jrd.2015-149 | |||||
| 関連名称 | Journal of Reproduction and Development | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
