{"created":"2023-05-15T13:36:41.729066+00:00","id":186,"links":{},"metadata":{"_buckets":{"deposit":"1a9e86fc-cc49-4fbb-a76f-cf5c1e8bc4d0"},"_deposit":{"created_by":11,"id":"186","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"186"},"status":"published"},"_oai":{"id":"oai:repository.naro.go.jp:00000186","sets":["2:581:62","87:633:42"]},"author_link":["1467","2563","1868","2566","2565","2562"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"212","bibliographicPageStart":"209","bibliographicVolumeNumber":"62","bibliographic_titles":[{"bibliographic_title":"Journal of Reproduction and Development"},{"bibliographic_title":"Journal of Reproduction and Development","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The antioxidant effect of N, N-dimethylglycine (DMG) on in vitro-produced (IVP) bovine embryos was examined. After in vitro fertilization, presumptive zygotes were cultured with or without 0.1 μM DMG under different oxygen tensions. The percentage of embryos developing to the blastocyst stage was lowest under a 20% oxygen concentration without DMG, and it was significantly increased (P < 0.05) by applying a 5% oxygen concentration. Under the 20% oxygen concentration, supplementation of the medium with DMG significantly improved blastocyst development, which was nearly equal to that achieved under 5% oxygen without DMG. Furthermore, a tendentious increase (P = 0.06) in blastocyst cell numbers was observed when DMG was applied. In the second experiment, addition of H2O2 (0.5 mM) to the culture medium significantly (P < 0.01) reduced the percentage of embryos developing to the blastocyst stage. However, DMG supplementation prevented this reduction. In conclusion, DMG enhanced the invitro development of IVP bovine embryos by acting as an antioxidant. ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Society for Reproduction and Development"},{"subitem_publisher":"日本繁殖生物学会 "}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"26875568","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1262/jrd.2015-149","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"SC10201706140010"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of Reproduction and Development"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1262/jrd.2015-149 ","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(c)2016 Society for Reproduction and Development"},{"subitem_rights":"(c) 日本繁殖生物学会 "}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1348-4400","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TAKAHASHI, Toshikiyo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"SASAKI, Kouya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SOMFAI, Tamas","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"NAGAI, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"MANABE, Noboru","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"EDASHIGE, Keisuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-05"}],"displaytype":"detail","filename":"SC10201706140010_CCBYNCND_ja.pdf","filesize":[{"value":"522.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC10201706140010_CCBYNCND_ja.pdf","url":"https://repository.naro.go.jp/record/186/files/SC10201706140010_CCBYNCND_ja.pdf"},"version_id":"421ec308-a950-42bd-8b39-167a96b0b890"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Antioxidant","subitem_subject_scheme":"Other"},{"subitem_subject":"Bovine embryo","subitem_subject_scheme":"Other"},{"subitem_subject":"DMG","subitem_subject_scheme":"Other"},{"subitem_subject":"In vitro fertilization","subitem_subject_scheme":"Other"},{"subitem_subject":"N, N-Dimethylglycine","subitem_subject_scheme":"Other"},{"subitem_subject":"Antioxidant","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Bovine embryo","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DMG","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"In vitro fertilization","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"N, N-Dimethylglycine","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos"},{"subitem_title":"N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"11","path":["42","62"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-02-05"},"publish_date":"2018-02-05","publish_status":"0","recid":"186","relation_version_is_last":true,"title":["N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T17:04:25.128152+00:00"}