| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2016-07-28 |
| タイトル |
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|
タイトル |
Effect of consuming a purple-fleshed sweet potato beverage on health-related biomarkers and safety parameters in Caucasian subjects with elevated levels of blood pressure and liver function biomarkers: a 4-week, open-label, non-comparative trial |
| タイトル |
|
|
タイトル |
Effect of consuming a purple-fleshed sweet potato beverage on health-related biomarkers and safety parameters in Caucasian subjects with elevated levels of blood pressure and liver function biomarkers: a 4-week, open-label, non-comparative trial |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
anthocyanin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
blood pressure |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Caucasians |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
liver function biomarker |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
safety parameter |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
sweet potato |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
沖, 智之
狩野, 光芳
渡邉, 治
後藤, 一寿
BOELSMA, Esther
石川, 文保
須田, 郁夫
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
An open-label study with one treatment arm was conducted to investigate changes in health-related biomarkers (blood pressure and liver enzyme activity) and the safety of 4 weeks of consuming a purple-fleshed sweet potato beverage in Caucasian subjects. Twenty healthy adults, 18?70 years of age, with a body mass index >25 kg/m2, elevated blood pressure and elevated levels of liver function biomarkers consumed two cartons of purple-fleshed sweet potato beverage (125 ml, including 117 mg anthocyanin per carton) daily for 4 weeks. Hematology, serum clinical profile, dipstick urinalysis and blood pressure were determined before consumption, at 2 and 4 weeks of consumption and after a 2-week washout period. A trend was found toward lowering systolic blood pressure during the treatment period (p=0.0590). No significant changes were found in diastolic blood pressure throughout the study period. Systolic blood
pressure was significantly lower after 4 weeks of consumption compared with before consumption (p=0.0125) and was significantly higher after the 2-week washout period compared with after consumption (p=0.0496). The serum alanine aminotransferase level significantly increased over time, but aspartate aminotransferase and γ-glutamyltransferase levels stayed within the normal range of reference values. Safety parameters of the blood and urine showed no clinically relevant changes. The consumption of a purple-fleshed sweet potato beverage for 4 weeks resulted in no clinically relevant changes in safety parameters of the blood and urine and showed a trend toward lowering systolic blood pressure. |
| 書誌情報 |
Bioscience of Microbiota, Food and Health
en : Bioscience of Microbiota, Food and Health
巻 35,
号 3,
p. 129-136,
発行日 2016-07-28
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| 出版者 |
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出版者 |
BMFH Press |
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2186-3342 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.12938/bmfh.2015-026 |
| 情報源 |
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関連名称 |
SC10201706190001 |
| 関連サイト |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.12938/bmfh.2015-026 |
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関連名称 |
Bioscience of Microbiota, Food and Health |
| 著者版フラグ |
|
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
SC10201706190001.pdf (639.2 kB)
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