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両親媒性環境下の疎水性蛋白質の分子集合状態の特性評価
https://doi.org/10.24514/00002696
https://doi.org/10.24514/00002696bd6393a5-df59-4a07-ba38-9d06999e0c8c
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文01 / Departmental Bulletin Original Article(1) | |||||||||||
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公開日 | 2019-10-03 | |||||||||||
タイトル | ||||||||||||
タイトル | 両親媒性環境下の疎水性蛋白質の分子集合状態の特性評価 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | Characterization of the Molecular Assembly of a Hydrophobic Integral Membrane Protein under Amphiphilic Conditions | |||||||||||
言語 | ||||||||||||
言語 | jpn | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | departmental bulletin paper | |||||||||||
ID登録 | ||||||||||||
ID登録 | 10.24514/00002696 | |||||||||||
ID登録タイプ | JaLC | |||||||||||
著者 |
渡邊, 康
× 渡邊, 康× 猪子, 洋二
WEKO
6768
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Protein characterization is indispensable in the various fields including life and food science. In this study, the preliminary results will be reported about the molecular assembly of a hydrophobic integral membrane protein sarcoplasmic reticulum CaATPase in the presence of surfactant/lipid mixed micelles, by using solution scattering methods such as the low-angle laser light scattering photometry combined with high performance gel chromatography, and synchrotron radiation solution X-ray scattering measurements. The results suggested that protein assemblies may play an important role in the function of this hydrophobic protein. | |||||||||||
抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | 蛋白質の関連する多様な分野において, 蛋白質の特性解析は蛋白質の素材としての有効利用に資することが期待される. 対象となる蛋白質は必ずしも水溶性でなく,水に単独では溶けない疎水性である場合もあり, このような蛋白質の構造研究は蛋白質の新たな物性の探索にも必要と思われる. 本研究では, 疎水性蛋白質として骨格筋小胞体膜蛋白質CaATPaseを対象に, 非イオン性界面活性剤と脂質共存下の可溶化蛋白質の溶液散乱測定を試みた. その結果, 本疎水性蛋白質の機能発現には高次会合体形成が重要であることが示唆された. | |||||||||||
書誌情報 |
食品総合研究所研究報告 en : Report of National Food Research Institute 巻 71, p. 33-37, 発行日 2007-03-01 |
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出版者 | ||||||||||||
出版者 | 農業・食品産業技術総合研究機構 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 0301-9780 | |||||||||||
DOI | ||||||||||||
関連タイプ | isIdenticalTo | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | 10.24514/00002696 | |||||||||||
著者版フラグ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |