@article{oai:repository.naro.go.jp:00002929,
 author = {後藤, 真生 and GOTO, Masao and 東, 照雄 and AZUMA, Teruo and 矢部, 希見子 and YABE, Kimiko},
 journal = {食品総合研究所研究報告, Report of National Food Research Institute},
 month = {Mar},
 note = {Enzyme activities of aflatoxin B_1 (AFB_1) reductase catalyzing the reaction from AFB_1 to aflatoxicol (AFL) and AFL dehydrogenase catalyzing the reaction from AFL to AFB_1 were investigated using cell-free systems from livers of rat Rattus norvegicus, horse mackerel Trachurus japonicus, and rainbow trout Oncorhynchus mykiss. The rat liver showed slight AFB_1 reductase activity, whereas the latter two fish livers showed remarkable activities. No significant differences in the enzyme activities were observed between male and female of the rainbow trouts. Characterization of the two enzyme activities suggested that they were different enzymes in the cells, which were exclusively involved in the different reactions, respectively., ニジマス, アジ, ラットの肝臓cytosolを用いて, アフラトキシンB_1  (AFB_1) からアフラトキシコール (AFL) への変換及びその逆反応の酵素活性を調べた. AFL形成活性は魚類において顕著な活性が見られたが, ラットではほとんど活性が認められなかった. それに対してAF生産反応はいずれの種でも顕著な活性が認められ, 3種で大差はみられなかった. ニジマス肝臓の酵素活性には雌雄差は認められなかった. ニジマスの肝臓cytosolでは両酵素活性は異なるpH依存性や温度依存性を示し, さらに両酵素活性について部分精製を試みたところ, 精製過程で両活性は異なる挙動を示した. 以上の結果から, これらの活性は異なる酵素によって触媒されることが示唆された.},
 pages = {67--70},
 title = {アフラトキシンB1とアフラトキシコールの変換反応に関与する肝臓酵素},
 volume = {71},
 year = {2007},
 yomi = {ゴトウ, マサオ and アズマ, テルオ and ヤベ, キミコ}
}