@article{oai:repository.naro.go.jp:00002766,
 author = {佐藤, 留美 and SATO, Rumi and 島, 純 and SHIMA, Jun and 鈴木, チセ and SUZUKI, Chise and 百瀬, 洋夫 and MOMOSE, Hiroh and 川本, 伸一 and KAWAMOTO, Shin-ichi},
 journal = {食品総合研究所研究報告, Report of National Food Research Institute},
 month = {Mar},
 note = {Bacteriocins are a heterogenous group of antimicrobial peptides and proteins produced by lactic acid bacteria(LAB) that inhibit the growth of closely related species. The stock strains of LAB in National Food Reseach Institute and Jissen Women's University were tested for the prodution of antimicrobial activity using a agar well diffusion assay against four species of Lactobacillus, Enterococcus faecium, and Bacillus subtilis as the indicator strains. Of 169 LAB strains tested, 8 strains were identified that inhibited the growth of at least one of the LAB indicator strains. They were E.faecalis NFRI7001, E.faecium NFRI7031, L.plantarum NFRI7313, L.sake NFRI7317, L.curvatus NFRI7352 and NFRI7372, L.casei K-1 and strain c5-1, most of which are food-borne bacteria. The antimicrobial compounds produced by these LAB strains except L.casei K-1 were all protease-sensitive, suggesting that the LAB strains were considered to produce bacteriocins. L.casei K-l produced a protease-resistant antimicrobial compound., 乳酸菌が産生するバクテリオシンは, 近縁の種の生育阻害を引き起こす蛋白質・ペプチド性の抗菌性物質である。食品総合研究所微生物バンク保存乳酸菌株98株と実践女子大学食品加工学研究室保存乳酸菌71株の計169株に関してLactobacillus属の4株, Enterococcus faeciumとBacillus subtilisを指示菌として用いた抗菌物質生産菌のスクリーニングを行った。その結果,  E.faecalis NFRI7001, E.faecmm NFRI7031, L.plantarum NFRI7313, L.sake NFRI7317, L.curvatus NFRI7352, L.curvatus NFRl7372, L.casei K-1, c5-1の計8株が用いた乳酸菌指示菌に対して抗菌性を示した。L.casei K-1の生産する抗菌物質は蛋白質分解酵素に耐性を示した。一方, 他の7菌株の抗菌活性は全て, 蛋白質分解酵素処理により消失した。以上のことから, これら7菌株は蛋白質・ペプチド性のバクテリオシンの生産菌であることが示唆された。},
 pages = {15--20},
 title = {微生物バンク等保存乳酸菌株のバクテリオシン生産性を指標とした特性評価},
 volume = {66},
 year = {2002},
 yomi = {サトウ, ルミ and シマ, ジュン and スズキ,  チセ and モモセ, ヒロオ and カワモト, シンイチ}
}