{"created":"2023-05-15T13:38:35.578926+00:00","id":2569,"links":{},"metadata":{"_buckets":{"deposit":"260a55b1-90a5-4ac1-b18f-b9a5bde5d651"},"_deposit":{"created_by":11,"id":"2569","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2569"},"status":"published"},"_oai":{"id":"oai:repository.naro.go.jp:00002569","sets":["87:639:640:19:383"]},"author_link":["6529","6528","2285"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"8","bibliographicPageStart":"1","bibliographicVolumeNumber":"124","bibliographic_titles":[{"bibliographic_title":"農研機構研究報告　動物衛生研究部門"},{"bibliographic_title":"Bulletin of the NARO, National Institute of Animal Health","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"衛生状態が異なる2つの養豚農場において肥育された豚の血清および口腔液を材料とし，各種病原体の浸潤状況をPCR およびELISA により，また，ストレスマーカーとしてIL-18，Cortisol およびIgA をELISA により調査した。血清中にPorcine reproductive and respiratory syndrome virus（PRRSV） およびSalmonella typhimurium（ ST） O4 抗体が検出され，かつ口腔液中にPRRSVおよびSwine influenza virus（SIV）遺伝子が検出されたH 農場の豚群では，いずれも陰性であったX 農場の豚群に比べて血清中IL-18 が有意に高かった。慢性ストレス条件下で低下するとされる血清中IgA はH 農場の豚群では低値のまま抑えられる傾向にあった。実際に，試験期間中のH 農場の事故率はX 農場に比べ約1.4 倍高く，X 農場に比べてH 農場では，一日あたりの増体成績も低く，出荷日齢も遅れたことは，H 農場の衛生状態の悪さが反映されていたと考えられた。以上の結果より，血清中IL-18 の定期的なモニタリングは養豚農場の衛生状態を評価するための有用な指標の一つとなりうると考えられた。","subitem_description_type":"Abstract"},{"subitem_description":"To evaluate the hygiene status of two different pig production farms, their pathogen invasion status was determined by PCR (Porcine reproductive and respiratory syndrome virus (PRRSV), Porcine circovirs type 2 (PCV2), Swine influenza virus (SIV)) and ELISA (PRRSV, Salmonella Choleraesuis (SC), Salmonella typhimurium (ST), Mycoplasma hyopneumoniae (Mhp)) of serum or of oral fluids collected from each group in a pen by using a cotton rope. Stress markers in the serum and oral fluids were measured by ELISA (IL-18, cortisol, IgA). Analyses for major pig viral and bacterial pathogens revealed anti-PRRSV and anti-ST O4 antibodies in the serum and positivity for PRRSV and SIV antigens in the oral fluids on farm H, but testing for serum antibodies and antigens in oral fluids on farm X was negative. Stress marker analysis showed that serum IL-18 concentrations were significantly higher in the pigs on farm H than in those on farm X. Serum IgA levels on farm H remained low, whereas those on farm X increased with age. The mortality rate on farm H was 1.4 times that on farm X. Daily gain was lower on farm H, and the date of shipping to market was extended on this farm. These results suggested that periodic monitoring of serum IL-18 can be a useful stress indicator for evaluating the hygiene status of pig production farms.","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24514/00002462","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"国立研究開発法人 農業・食品産業技術総合研究機構"},{"subitem_publisher":"National Agriculture and Food Research Organization (NARO)"}]},"item_10002_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.24514/00002462 ","subitem_relation_type_select":"DOI"}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2432-7875","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"矢ヶ部, 陽子"},{"creatorName":"ヤカベ, ヨウコ","creatorNameLang":"ja-Kana"},{"creatorName":"YAKABE, Yoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高萩, 陽一"},{"creatorName":"タカハギ, ヨウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"TAKAHAGI, Yoichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宗田, 吉広"},{"creatorName":"ムネタ, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"MUNETA, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-05-15"}],"displaytype":"detail","filename":"niah_report124-1.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","license_note":"© 国立研究開発法人 農業・食品産業技術総合研究機構\nNational Agriculture and Food Research Organization, Japan\n","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"niah_report124-1","url":"https://repository.naro.go.jp/record/2569/files/niah_report124-1.pdf"},"version_id":"9b639451-07d0-4533-8232-e9dac3c7c4ad"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hygiene conditions","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-18","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pathogen invasion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"serum","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"血清中Interleukin-18 (IL-18) の定期的なモニタリングは養豚農場の衛生状態を評価するための有用な1 指標となりうる─ 2 養豚農場の比較による実証試験の一例─","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"血清中Interleukin-18 (IL-18) の定期的なモニタリングは養豚農場の衛生状態を評価するための有用な1 指標となりうる─ 2 養豚農場の比較による実証試験の一例─"},{"subitem_title":"Serum interleukin-18 is a potential marker for evaluating hygiene status on pig farms: comparison of two pig farms","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"11","path":["383"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-15"},"publish_date":"2019-05-15","publish_status":"0","recid":"2569","relation_version_is_last":true,"title":["血清中Interleukin-18 (IL-18) の定期的なモニタリングは養豚農場の衛生状態を評価するための有用な1 指標となりうる─ 2 養豚農場の比較による実証試験の一例─"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T15:23:30.235833+00:00"}