{"created":"2023-05-15T13:38:33.256576+00:00","id":2521,"links":{},"metadata":{"_buckets":{"deposit":"c5524adf-59ff-434b-b03a-5f908eae2bf4"},"_deposit":{"created_by":11,"id":"2521","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2521"},"status":"published"},"_oai":{"id":"oai:repository.naro.go.jp:00002521","sets":["2:581:107","87:654:46"]},"author_link":["1494"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Gene Expression Patterns"},{"bibliographic_title":"Gene Expression Patterns","bibliographic_titleLang":"en"}]}]},"item_10001_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"author manuscript ","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Insect embryogenesis is divided into long and short/intermediate germ types. The long germ type may exhibit Drosophila-like hierarchical segmentation mechanisms, whereas the short/intermediate type assumes some repeating mechanisms that are considered to be ancestral. Embryogenesis in Bombyx mori possesses both characteristics. Here, Bombyx ovo homolog (Bm-ovo) was identified as a gene involved in segmentation. ovo is a Drosophila gene that encodes a zinc finger transcription factor and studies on its homolog functions in other systems have suggested that it acts as a switch to enable the initiation of differentiation from a progenitor cell state. This is the first description for ovo homologs being involved in insect segmentation. Bm-ovo is expressed dynamically during embryogenesis in a pattern that resembles that of gap and pair-rule genes. In Bm-ovo RNAi knockdown embryos, posterior segmentation does not proceed. In addition, defects in anterior segments are observed. In Bm-wnt1 knockdown embryos, the Bm-ovo expression pattern was changed, suggesting that Bm-wnt1 is an upstream regulator of Bm-ovo. The involvement of Bm-ovo may represent a novel ancestral step under the control of wnt genes in insect segmentation: this step may resemble those operating in cell differentiation processes.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.gep.2017.10.002","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"SC30201804040067"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"NARO成果DBa"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"この論文は出版社版ではありません。引用の際には出版社版をご利用ください。"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"This is not the published version. Please cite only the published version. "}]},{"subitem_relation_name":[{"subitem_relation_name_text":"Green open Access"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"This journal has an embargo period of 12 months."}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Gene Expression Patterns"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.gep.2017.10.002","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":" The Author(s) "},{"subitem_rights":"2017 Published by Elsevier Ltd. "}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1567-133X","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中尾, 肇"},{"creatorName":"ナカオ, ハジメ","creatorNameLang":"ja-Kana"},{"creatorName":"NAKAO, Hajime","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-02-01"}],"displaytype":"detail","filename":"SC30201804040067_PostPrint.pdf","filesize":[{"value":"5.9 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC30201804040067_PostPrint","url":"https://repository.naro.go.jp/record/2521/files/SC30201804040067_PostPrint.pdf"},"version_id":"b0352657-3b1b-445e-a8e9-117636ba6e2f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bombyx","subitem_subject_scheme":"Other"},{"subitem_subject":"ovo","subitem_subject_scheme":"Other"},{"subitem_subject":"wnt1","subitem_subject_scheme":"Other"},{"subitem_subject":"RNAi","subitem_subject_scheme":"Other"},{"subitem_subject":"segmentation","subitem_subject_scheme":"Other"},{"subitem_subject":"pair-rule genes","subitem_subject_scheme":"Other"},{"subitem_subject":"Bombyx","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ovo","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"wnt1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"RNAi","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"segmentation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pair-rule genes","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A  Bombyx  homolog of  ovo  is a segmentation gene that acts downstream of  Bm-wnt1 ( Bombyx wnt1  homolog)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A  Bombyx  homolog of  ovo  is a segmentation gene that acts downstream of  Bm-wnt1 ( Bombyx wnt1  homolog)"},{"subitem_title":"A  Bombyx  homolog of  ovo  is a segmentation gene that acts downstream of  Bm-wnt1 ( Bombyx wnt1  homolog)","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"11","path":["46","107"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-14"},"publish_date":"2019-05-14","publish_status":"0","recid":"2521","relation_version_is_last":true,"title":["A  Bombyx  homolog of  ovo  is a segmentation gene that acts downstream of  Bm-wnt1 ( Bombyx wnt1  homolog)"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T15:49:22.722075+00:00"}