@article{oai:repository.naro.go.jp:00002521,
 author = {中尾, 肇 and NAKAO, Hajime},
 journal = {Gene Expression Patterns, Gene Expression Patterns},
 month = {Jan},
 note = {author manuscript, Insect embryogenesis is divided into long and short/intermediate germ types. The long germ type may exhibit Drosophila-like hierarchical segmentation mechanisms, whereas the short/intermediate type assumes some repeating mechanisms that are considered to be ancestral. Embryogenesis in Bombyx mori possesses both characteristics. Here, Bombyx ovo homolog (Bm-ovo) was identified as a gene involved in segmentation. ovo is a Drosophila gene that encodes a zinc finger transcription factor and studies on its homolog functions in other systems have suggested that it acts as a switch to enable the initiation of differentiation from a progenitor cell state. This is the first description for ovo homologs being involved in insect segmentation. Bm-ovo is expressed dynamically during embryogenesis in a pattern that resembles that of gap and pair-rule genes. In Bm-ovo RNAi knockdown embryos, posterior segmentation does not proceed. In addition, defects in anterior segments are observed. In Bm-wnt1 knockdown embryos, the Bm-ovo expression pattern was changed, suggesting that Bm-wnt1 is an upstream regulator of Bm-ovo. The involvement of Bm-ovo may represent a novel ancestral step under the control of wnt genes in insect segmentation: this step may resemble those operating in cell differentiation processes.},
 pages = {1--7},
 title = {A  Bombyx  homolog of  ovo  is a segmentation gene that acts downstream of  Bm-wnt1 ( Bombyx wnt1  homolog)},
 volume = {27},
 year = {2018},
 yomi = {ナカオ, ハジメ}
}