@article{oai:repository.naro.go.jp:00002498,
 author = {中川, 博之 and NAKAGAWA, Hiroyuki},
 issue = {6},
 journal = {Bioorganic & Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry Letters},
 month = {Apr},
 note = {The isoleucine conjugate of 12-oxo-phytodienoic acid (OPDA-Ile), a new member of the jasmonate family, was recently identified in Arabidopsis thaliana and might be a signaling molecule in plants. However, the biosynthesis and function of OPDA-Ile remains elusive. This study reports an in vitro enzymatic method for synthesizing OPDA-Ile, which is catalyzed by reactions of lipoxygenase (LOX), allene oxide synthase (AOS), and allene oxide cyclase (AOC) using isoleucine conjugates of  α-linolenic acid (LA-Ile) as the substrate. A. thaliana fed LA-Ile exhibited a marked increase in the OPDA-Ile concentration. LA-Ile was also detected in A. thaliana. Furthermore, stable isotope labelled LA-Ile was incorporated into OPDA-Ile. Thus, OPDA-Ile is biosynthesized via the cyclization of LA-Ile in A. thaliana.},
 pages = {1020--1023},
 title = {Biosynthesis and in vitro enzymatic synthesis of the isoleucine conjugate of 12-oxo-phytodienoic acid from the isoleucine conjugate of α-linolenic acid},
 volume = {28},
 year = {2018},
 yomi = {ナカガワ, ヒロユキ}
}