{"created":"2023-05-15T13:38:06.182861+00:00","id":1895,"links":{},"metadata":{"_buckets":{"deposit":"a8591841-4d9e-4bc1-b3ed-92e84a7c0c5c"},"_deposit":{"created_by":12,"id":"1895","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"1895"},"status":"published"},"_oai":{"id":"oai:repository.naro.go.jp:00001895","sets":["87:639:640:134:328"]},"author_link":["1029","6079","6075","1572","1661","6080","1020","6076","6072","1198","2137","6078","5979"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-03-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"16","bibliographicPageStart":"9","bibliographicVolumeNumber":"109","bibliographic_titles":[{"bibliographic_title":"動物衛生研究所研究報告"},{"bibliographic_title":"Bulletin of the National Institute of Animal Health","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Postweaning multisystemic wasting syndrome (PMWS) is an emerging infectious disease associated with the infection of porcine circovirus type 2 (PCV2), which was newly recognized in Canada in 1998. Since there was no available information on the actual condition regarding PMWS in Japan, specific methods for diagnosis of this syndrome were developed, and the pathogenesis of PMWS was studied by a pathophysiological analysis of the affected pigs, an experimental infection of PCV2, and a survey for the prevalence of PMWS and PCV2. In the results, the peripheral lymphocyte count was reduced in pigs affected with PMWS, and pretreatment with dexamethasone exacerbated PCV2 multiplication and lesion formation in the lymphoid tissue of the pigs inoculated with PCV2, suggesting that the immune status of the host might be related to the pathogenesis of PMWS. The epidemiological studies demonstrated that PCV2 is widely distributed in pigs and, furthermore, there is a large population with subclinical infection.\n","subitem_description_type":"Abstract"},{"subitem_description":"離乳後多臓器性発育不良症候群（ p o s t w e a n i n g multisystemic wasting syndrome：PMWS）は, 1998年にカナダで新たに見つかったブタサーコウイルス2型（PCV2）が関与する豚の新興感染病である. わが国におけるPMWSの実態を明らかにするために, PCV2抗体の検出法, PCRによる遺伝子診断法および免疫組織学的検出法を開発し, PMWS発症豚の病態解析, 実験感染および全国規模のPMWSの実態調査を行った. その結果, PMWS発症豚の抹消血リンパ球は減少していること, ならびにデキサメタゾンの前投与によってPCV2感染豚のリンパ組織におけるPCV2の増殖と病変形成が増強されることを明らかにし,  PMWSの病理発生に宿主の免疫状態が関連する可能性を示唆した. 疫学調査結果から, PCV2がわが国に広く浸潤していること, また, PCV2は検出されるがPMWS病変を持たない豚が高率に存在することが明らかとなった. \n","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24514/00001854","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"独立行政法人 農業技術研究機構 動物衛生研究所"}]},"item_10002_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.24514/00001854","subitem_relation_type_select":"DOI"}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1347-2542","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"川嶌, 健司"},{"creatorName":"カワシマ, ケンジ","creatorNameLang":"ja-Kana"},{"creatorName":"KAWASHIMA, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"恒光, 裕"},{"creatorName":"ツネミツ, ヒロシ","creatorNameLang":"ja-Kana"},{"creatorName":"TSUNEMITSU, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"堀野, 理恵子"},{"creatorName":"ホリノ, リエコ","creatorNameLang":"ja-Kana"},{"creatorName":"HORINO, Rieko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"勝田, 賢"},{"creatorName":"カツダ, ケン","creatorNameLang":"ja-Kana"},{"creatorName":"KATSUDA, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"庄司, 智太郎"},{"creatorName":"ショウジ, トモタロウ","creatorNameLang":"ja-Kana"},{"creatorName":"SHOJI, Tomotaro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小野寺, 利幸"},{"creatorName":"オノデラ, トシユキ","creatorNameLang":"ja-Kana"},{"creatorName":"ONODERA, Toshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"播谷, 亮"},{"creatorName":"ハリタニ, マコト","creatorNameLang":"ja-Kana"},{"creatorName":"HARITANI, Makoto","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"村上, 洋介"},{"creatorName":"ムラカミ, ヨウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"MURAKAMI, Yosuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"久保, 正法"},{"creatorName":"クボ, マサノリ","creatorNameLang":"ja-Kana"},{"creatorName":"KUBO, Masanori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"池田, 秀利"},{"creatorName":"イケダ, ヒデトシ","creatorNameLang":"ja-Kana"},{"creatorName":"IKEDA, Hidetoshi","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"加来, 義浩"},{"creatorName":"カク, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"KAKU, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"木村, 久美子"},{"creatorName":"キムラ, クミコ","creatorNameLang":"ja-Kana"},{"creatorName":"KIMURA, Kumiko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"谷村, 信彦"},{"creatorName":"タニムラ, ノブヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"TANIMURA, Nobuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-03-19"}],"displaytype":"detail","filename":"niah_report_No109p9-16p.pdf","filesize":[{"value":"472.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"niah_report_No109p9-16p.pdf","url":"https://repository.naro.go.jp/record/1895/files/niah_report_No109p9-16p.pdf"},"version_id":"4196df2b-57f7-4cef-b444-250c779bc22f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"わが国の豚における離乳後多臓器性発育不良症候群 (PMWS) の実態解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"わが国の豚における離乳後多臓器性発育不良症候群 (PMWS) の実態解明"},{"subitem_title":"Postweaning multisystemic wasting syndrome (PMWS) in pigs in Japan: Clinical manifestation of the diseased pigs, experimental infection of porcine circovirus type 2 (PCV2), and epidemiological investigations of PCV2 and PMWS","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"12","path":["328"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-03-22"},"publish_date":"2019-03-22","publish_status":"0","recid":"1895","relation_version_is_last":true,"title":["わが国の豚における離乳後多臓器性発育不良症候群 (PMWS) の実態解明"],"weko_creator_id":"12","weko_shared_id":12},"updated":"2023-05-15T15:30:26.285194+00:00"}