{"created":"2023-05-15T13:36:40.671425+00:00","id":164,"links":{},"metadata":{"_buckets":{"deposit":"4a3030e7-313f-4ba5-997a-c6fb144c6b28"},"_deposit":{"created_by":11,"id":"164","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"164"},"status":"published"},"_oai":{"id":"oai:repository.naro.go.jp:00000164","sets":["2:581:68","87:639:43"]},"author_link":["2503","1633","678","2189","1589","1002","1393"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-06","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"169","bibliographicPageStart":"165","bibliographicVolumeNumber":"106","bibliographic_titles":[{"bibliographic_title":"Research in Veterinary Science"},{"bibliographic_title":"Research in Veterinary Science","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A full-length infectious cDNA clone of the genome of a foot-and-mouth disease virus isolated from the 2010 epidemic in Japan was constructed and designated pSVL-f02. Transfection of Cos-7 or IBRS-2 cells with this clone allowed the recovery of infectious virus. The recovered virus had the same in vitro characterization as the parental virus with regard to antigenicity in neutralization and indirect immunofluorescence tests, plaque size and one-step growth. Pigs were experimentally infected with the parental virus or the recombinant virus recovered from pSVL-f02 transfected cells. There were no significant differences in clinical signs or antibody responses between the two groups, and virus isolation and viral RNA detection from clinical samples were similar. Virus recovered from transfected cells therefore retained the in vitro characteristics and the in vivo pathogenicity of their parental strain. This cDNA clone should be a valuable tool to analyze determinants of pathogenicity and mechanisms of virus replication, and to develop genetically engineered vaccines against foot-and-mouth disease virus.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"27234555","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.rvsc.2016.03.017","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"SC30201707130014"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Research in Veterinary Science"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.rvsc.2016.03.017","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_18":{"attribute_name":"他の資源との関係","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"author manuscript"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(C) 2016 Elsevier Ltd. "},{"subitem_rights":"Green open Access"},{"subitem_rights":"この論文は出版社版ではありません。引用の際には出版社版をご利用ください。"},{"subitem_rights":"This is not the published version. Please cite only the published version."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0034-5288","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"西, 達也"},{"creatorName":"ニシ, タツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"NISHI, Tatsuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2189","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40739306","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40739306"},{"nameIdentifier":"ultra1124","nameIdentifierScheme":"researchmap","nameIdentifierURI":"http://researchmap.jp/ultra1124"}]},{"creatorNames":[{"creatorName":"小野里, 洋行"},{"creatorName":"オノザト, ヒロユキ","creatorNameLang":"ja-Kana"},{"creatorName":"ONOZATO, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2503","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50508314","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50508314"}]},{"creatorNames":[{"creatorName":"大橋, 誠一"},{"creatorName":"オオハシ, セイイチ","creatorNameLang":"ja-Kana"},{"creatorName":"OHASHI, Seiichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1589","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80355213","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80355213"},{"nameIdentifier":"_0705","nameIdentifierScheme":"researchmap","nameIdentifierURI":"http://researchmap.jp/_0705"}]},{"creatorNames":[{"creatorName":"深井, 克彦"},{"creatorName":"フカイ, カツヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"FUKAI, Katsuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"678","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70414729","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70414729"},{"nameIdentifier":"KatsuhikoFukai","nameIdentifierScheme":"researchmap","nameIdentifierURI":"http://researchmap.jp/KatsuhikoFukai"},{"nameIdentifier":"0000-0002-8422-1681","nameIdentifierScheme":"ORCID","nameIdentifierURI":"http://orcid.org/0000-0002-8422-1681"}]},{"creatorNames":[{"creatorName":"山田, 学"},{"creatorName":"ヤマダ, マナブ","creatorNameLang":"ja-Kana"},{"creatorName":"YAMADA, Manabu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1633","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50355195","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50355195"},{"nameIdentifier":"yamadam","nameIdentifierScheme":"researchmap","nameIdentifierURI":"http://researchmap.jp/yamadam"}]},{"creatorNames":[{"creatorName":"森岡, 一樹"},{"creatorName":"モリオカ, カズキ","creatorNameLang":"ja-Kana"},{"creatorName":"MORIOKA, Kazuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1393","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70355189","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70355189"},{"nameIdentifier":"read0080537","nameIdentifierScheme":"researchmap","nameIdentifierURI":"http://researchmap.jp/read0080537"}]},{"creatorNames":[{"creatorName":"菅野, 徹"},{"creatorName":"カンノ, トオル","creatorNameLang":"ja-Kana"},{"creatorName":"KANNO, Toru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1002","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80355205","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80355205"},{"nameIdentifier":"read0004113","nameIdentifierScheme":"researchmap","nameIdentifierURI":"http://researchmap.jp/read0004113"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-22"}],"displaytype":"detail","filename":"SC30201707130014 _postprint.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC30201707130014 _postprint.pdf ","url":"https://repository.naro.go.jp/record/164/files/SC30201707130014 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strain","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Construction and characterization of a full-length infectious cDNA clone of foot-and-mouth disease virus strain O/JPN/2010 isolated in Japan in 2010","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Construction and characterization of a full-length infectious cDNA clone of foot-and-mouth disease virus strain O/JPN/2010 isolated in Japan in 2010"},{"subitem_title":"Construction and characterization of a full-length infectious cDNA clone of foot-and-mouth disease virus strain O/JPN/2010 isolated in Japan in 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